Pharmacology and pharmaceutical sciences

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Designing mRNA formulations for vaccine development

thesis first posted online on 2025-04-17

Asuka Takanashi

Permanent

FILES UNDER EMBARGO

Biomarker Discovery in Parkinson’s Disease; A Focus on the Diagnostic Value of the Sphingolipid Pathway in Early-stage Diagnosis

thesis first posted online on 2025-04-09

Ali Esfandiary

Investigating human milk as a lipid-based formulation for the delivery of poorly water-soluble drugs in paediatric populations

thesis first posted online on 2025-02-28

Ellie Ponsonby-Thomas

Permanent

FILES UNDER EMBARGO

New Approaches to Treat Organ Failure via Inhibition of Pancreatic Enzymes in the Gut and Gut Lymph

thesis first posted online on 2025-02-13

Zijun Lu

Permanent

FILES UNDER EMBARGO

Novel GPR52 Agonists for the Treatment of Schizophrenia

thesis first posted online on 2024-12-18

Jiyuan Che

Permanent

FILES UNDER EMBARGO

Exploring Polymer-Lipids in Lipid Nanoparticle Formulations

thesis first posted online on 2024-11-22

Dayangku Nordiyana Binti Pengiran Hassanel

Design and Exploration of Sphingolipid Mimetics in Lipid Metabolism

thesis first posted online on 2024-10-25

MUN CHUNG DOROTHY KO

Permanent

FILES UNDER EMBARGO

Design and Synthesis of Novel CNS-Penetrant 18F Radioligands of MERTK for the Imaging of Multiple Sclerosis

thesis first posted online on 2024-10-25

Lian Xue

Investigations into VprBP Functions, Engagement and Inhibition

thesis first posted online on 2024-10-11

Decoding G Protein-Coupled Receptor Signalling Fingerprints to Identify Novel Therapeutic Targets for Cardiac Fibrosis Treatment

thesis first posted online on 2024-09-23

Joel Wake Coffie

Permanent

FILES UNDER EMBARGO

Molecular and structural characterisation of GPR52 functional selectivity and its implications in schizophrenia

thesis first posted online on 2024-08-30

YAO LU

Permanent

FILES UNDER EMBARGO

Investigation of atomization and micronization of biomacromolecules for pulmonary drug delivery

thesis first posted online on 2024-08-28

Hao Miao

Modifying Pasireotide Analogues For Improved Oral Peptide Delivery

thesis first posted online on 2024-08-25

Celine Yamfa Hung

Permanent

FILES UNDER EMBARGO

The rational design of Zika protease inhibitors

thesis first posted online on 2024-05-26

JACK PHELPS

Permanent

FILES UNDER EMBARGO

Development of EcDsbA Inhibitors Using Fragment-Based Design Strategies

thesis first posted online on 2024-05-24

YILDIZ TASDAN

Metacognitive scaffolding in chemistry education: Investigating student problem-solving approaches and instructor perspectives and practices

thesis first posted online on 2024-05-15

KIMBERLY VO

Therapeutic Properties of the Designer Cytokine IC7Fc to Treat Metabolic Diseases

thesis first posted online on 2024-05-06

JINGJING ZHAO

Development of Foldamers for Peptide Receptor Radionuclide Therapy of NPY1 Tumours

thesis first posted online on 2024-05-01

AMIT HETSRON

Permanent

FILES UNDER EMBARGO

Synthesis and Evaluation of 2,4-Diamino-1,3,5-triazines as Bioactive Agents against Triple-negative Breast Cancer Cells

thesis first posted online on 2024-04-18

HAN YIN LIM

Allosteric Modulation at the Delta Opioid Receptor for the Treatment of Gastrointestinal Motility Disorders

thesis first posted online on 2024-03-17

Design of Novel Cyclic Peptidomimetics – Melanocortin Peptides as An Example

thesis first posted online on 2024-02-28

WENXIAO YUE

Characterisation and evaluation of pro-resolving G protein-coupled receptors (GPCRs) in resolution of inflammation

thesis first posted online on 2024-01-28

JULIA SOYOUNG PARK

Permanent

FILES UNDER EMBARGO

The Potential Use Of Mangrove-Derived Streptomyces sp. As Probiotics Against Vibrio Parahaemolyticus Infection In Aquaculture Farming

thesis first posted online on 2024-01-12

JOANNA XUAN HUI GOH

Permanent

FILES UNDER EMBARGO

Optimisation of Nanoparticles for Crossing the Blood-brain Barrier Using a Microfluidic Chip Model

thesis first posted online on 2023-12-04

WEISEN ZHANG

Permanent

FILES UNDER EMBARGO

Characterisation of Endogenous Tachykinin Signalling at the Neurokinin-1 Receptor and Determining its Role in Neurological Outcomes after Experimental Stroke

thesis first posted online on 2023-10-08

ROISIN EIMIR MCCAGUE

Lipidation of brush polyethylene glycol polymers to extend plasma half-life and promote lymphatic uptake

thesis first posted online on 2023-10-08

MOHAMMAD SULTAN MOHAMMAD ABDALLAH

Permanent

FILES UNDER EMBARGO

Development and optimisation of lymph-directing prodrugs to enhance oral drug exposure

thesis first posted online on 2023-10-03

XIAOTONG ZHOU

Electrochemical biosensing to unveil the role of exosomes as cancer biomarkers

thesis first posted online on 2023-09-28

GRACE PEI CHIN

Profiling Glucagon-Like Peptide -1 Receptor Transducer Coupling, Signalling and Biased Agonism

thesis first posted online on 2023-09-12

JOHN TEYE AZIETAKU

Engineered vertically-aligned polymeric nanostructures for intracellular delivery to mammalian cells

thesis first posted online on 2023-08-17

HAO ZHE YOH

Delivering Micro-RNA (miRNA) via β-peptide Derived Biomaterial to Treat Ischemic Stroke

thesis first posted online on 2023-08-15

YI-KAI CHEN

Permanent

FILES UNDER EMBARGO

An exploration of oxytocin receptor signalling in the prostate and bladder: Implications for the treatment of benign prostatic hyperplasia and overactive bladder syndrome

thesis first posted online on 2023-08-08

MASROOR BADSHAH

Permanent

FILES UNDER EMBARGO

Discovery of a novel Melanocortin receptor 5 agonist for Type 1 Diabetes

thesis first posted online on 2023-07-18

REKHA SHANDRE MUGAN

The development of methods for the rapid assembly of diverse sp2- and sp3-rich scaffolds

thesis first posted online on 2023-07-17

SHUQI CHEN

Permanent

FILES UNDER EMBARGO

Antibody-functionalised porous silicon nanoparticles for delivering tumour antigens to dendritic cells

thesis first posted online on 2023-06-14

ANAL SANJAY DESAI

Modulating development and maturation of human embryonic stem cell-derived midbrain dopaminergic neurons using growth and survival factors

thesis first posted online on 2023-05-24

SHANTI MARLINA SIBUEA

Structure-Activity and Metabolic Relationships of 2-Aminobenzimidazole Antimalarials

thesis first posted online on 2023-05-24

JOMO KENYATTA NJUGUNA KIGOTHO

Dual incretin agonism in the treatment of Type 2 Diabetes and Obesity

thesis first posted online on 2023-04-24

VANESSA TING ZHEN KEE

Permanent

FILES UNDER EMBARGO

The Development of a New Class of Plasmodium falciparum M1 and M17 Inhibitors as Potential Antimalarials

thesis first posted online on 2023-04-17

MAHTA MANSOURI JAJAEI

The Design, Synthesis and Evaluation of Novel Metalloaminopeptidase Inhibitors

thesis first posted online on 2023-04-13

PETAR PATRICK STEPHEN CALIC