Monash University

Embargoed and Restricted Access

Reason: Under embargo until19 April 2025. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Synthesis and Evaluation of 2,4-Diamino-1,3,5-triazines as Bioactive Agents against Triple-negative Breast Cancer Cells

posted on 2024-04-18, 15:01 authored by HAN YIN LIM
The thesis contributes to developing new methods for preparing bioactive compounds with 2,4-diamino-1,3,5-triazine skeleton and potential applications as anticancer agents. The methods were effective for the synthesis of compounds with one, two, and three points of diversity. Some of the prepared molecules were highly active against breast cancer cells. The established structure-activity relationships will be useful for further drug design and development programs.


Campus location


Principal supervisor

Anton Dolzhenko

Additional supervisor 1

Alice Chuah Lay Hong

Year of Award


Department, School or Centre

School of Pharmacy (Malaysia)


Doctor of Philosophy

Degree Type



Faculty of Pharmacy and Pharmaceutical Sciences