Neural Mechanisms of Stages of Reward and Avoidance Decision Processes and Clinical Implication in Obsessive-Compulsive Disorder and Gambling Disorder

Using a novel probabilistic reward and avoidance learning task together with behavioural modelling and neuroimaging techniques, the present study was aimed to generate robust learning signal, thus, to examine brain activity associated with key steps of reward and loss processing. Further, application of the paradigm of behavioural modelling and neuroimaging technique, we were to examine brain activity associated with the aforementioned key steps of reward and loss processing in OCD and GD, and the correlation with the scales of impulsivity and compulsivity as well the clinical severity.