RahiniRagavanKakumanu_PHDThesis.pdf (5.3 MB)
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Investigating cardiovascular activities of animal venom

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thesis
posted on 17.09.2021, 07:29 by RAHINI RAGAVAN KAKUMANU
Venom is made up of a complex cocktail of toxins, many of which are harmful to humans. Many toxins have been well studied however the activity of proteins/peptides affecting the cardiovascular system are poorly understood. In this thesis, the cardiovascular effects of venom from different snake species and vampire bat were investigated. The mechanisms behind cardiovascular collapse (rapid drop in blood pressure) , and prolonged hypotension (gradual decrease in blood pressure) were examined and characterized. The mechanisms of actions of these venom components were further elucidated. The results of this thesis will provide us a better understanding of the envenoming of humans and potential treatment strategies.

History

Principal supervisor

Wayne Hodgson

Year of Award

2021

Department, School or Centre

Pharmacology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

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