L137 PhD_Thesis_Andrew_Guy_2018_Redacted.pdf (10.74 MB)
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Computational approaches for examining the impact of protein structure on malaria immunity

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thesis
posted on 21.03.2019, 00:05 by ANDREW JOHN GUY
This thesis examines the impact of protein three-dimensional (3D) structure on the development of adaptive immunity to malaria. This work has identified new bioinformatics approaches that highlight the prevalence and importance of disordered proteins, as well as new approaches for mapping critical characteristics onto protein 3D structures. These approaches have been applied to specific vaccine candidates, highlighting important regions to assist with vaccine design.

History

Principal supervisor

Paul Ramsland

Additional supervisor 1

Jack Richards

Additional supervisor 2

James Beeson

Year of Award

2018

Department, School or Centre

Immunology - Alfred

Additional Institution or Organisation

Burnet Institute

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences