Monash University
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Publications

  • The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
  • The mystery behind membrane insertion: A review of the complement membrane attack complex
  • Ancient but Not Forgotten: New Insights Into MPEG1, a Macrophage Perforin-Like Immune Effector
  • The first transmembrane region of complement component-9 acts as a brake on its self-assembly
  • Structural and functional characterisation of MACPF proteins in immunity
  • Challenges and approaches to studying pore-forming proteins
  • The cryo-EM structure of the human neurofibromin dimer reveals the molecular basis for neurofibromatosis type 1
  • Mining folded proteomes in the era of accurate structure prediction
  • The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
  • Structure of the metastatic factor P-Rex1 reveals a two-layered autoinhibitory mechanism
  • Single-molecule analysis of the entire perfringolysin O pore formation pathway
  • Helical ultrastructure of the metalloprotease meprin α in complex with a small molecule inhibitor
  • The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
  • Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically "actionable" signalling axis in triple negative breast cancer
  • Feed-forward stimulation of CAMK2 by the oncogenic pseudokinase PEAK1 generates a therapeutically ‘actionable’ signalling axis in triple negative breast cancer
  • LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR
  • Structure of the human TSC:WIPI3 lysosomal recruitment complex
  • Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer

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