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Understanding the role of Candida albicans Rpn4 in proteasome assembly and its link to cell membrane stress
thesisposted on 2021-11-16, 23:51 authored by Ka Pui Sharon Yau
Candida albicans is a highly adaptable human fungal pathogen that can cause superficial to serious infections. Incidences of antifungal resistance are increasing and pose a major concern to our healthcare system. This thesis examines the molecular components and pathways which enables Candida albicans to develop resistance and tolerance following exposure to antifungals.