Monash University

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Reason: Under embargo until 31 November 2023. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Understanding the role of Candida albicans Rpn4 in proteasome assembly and its link to cell membrane stress

posted on 2021-11-16, 23:51 authored by Ka Pui Sharon Yau
Candida albicans is a highly adaptable human fungal pathogen that can cause superficial to serious infections. Incidences of antifungal resistance are increasing and pose a major concern to our healthcare system. This thesis examines the molecular components and pathways which enables Candida albicans to develop resistance and tolerance following exposure to antifungals.


Principal supervisor

Ana Traven

Additional supervisor 1

Traude Beilharz

Year of Award


Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Biochemistry and Molecular Biology

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine, Nursing and Health Sciences