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Towards new treatments targeting parasitic nematodes

thesis
posted on 15.03.2019 by THUY GIANG LE
In parasites, anthelmintic resistance is a major concern globally. There is a high demand for new anthelmintics with new chemical entities and mode of action to circumvent this problem. Parasitic helminths (worms) can be targeted with small-molecule drugs, either directly, or via the attack on bacterial endosymbionts of the genus Wolbachia present in some species. This thesis focuses on the development of lead drug-like molecules with potent anthelmintic activity.

History

Principal supervisor

Jonathan Baell

Year of Award

2019

Department, School or Centre

Medicinal Chemistry

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences

Exports

Categories

Exports