File(s) under permanent embargo
Reason: Under embargo until March 2020. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library, or by emailing firstname.lastname@example.org
Towards new treatments targeting parasitic nematodes
thesisposted on 15.03.2019, 02:53 authored by THUY GIANG LE
In parasites, anthelmintic resistance is a major concern globally. There is a high demand for new anthelmintics with new chemical entities and mode of action to circumvent this problem. Parasitic helminths (worms) can be targeted with small-molecule drugs, either directly, or via the attack on bacterial endosymbionts of the genus Wolbachia present in some species. This thesis focuses on the development of lead drug-like molecules with potent anthelmintic activity.