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The structure and function of G protein-coupled receptors

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thesis
posted on 13.10.2021, 23:07 by PATRICK SEXTON
Membrane proteins are gatekeepers of cellular function with G protein-coupled receptors (GPCRs) that largest membrane protein family. This thesis describes the integrated application of study of GPCR structure with detailed molecular pharmacology and analytical pharmacological analysis of GPCRs and ligands to evolve our understanding of how activators differentially modulate GPCR function. This work is important for current and future drug discovery that targets this family of receptor proteins.

History

Campus location

Australia

Principal supervisor

Peter Betts

Year of Award

2021

Department, School or Centre

Biological Sciences

Course

Doctor of Science

Degree Type

HIGH_DOCTORATE

Faculty

Faculty of Science

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