L95 The role of vascular NADPH oxidase enzymes in influenza morbidity_Redacted.pdf (6.03 MB)
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The role of vascular NADPH oxidase enzymes in influenza morbidity

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posted on 2019-03-13, 22:22 authored by KESHIA SARAH HENDRICKS
Every year, up to half a million people lose their lives to influenza infection. Australia recently experienced the worst seasonal influenza epidemic since the 2009 Swine Flu pandemic. The hallmarks of serious cases of influenza infections include an exaggerated inflammatory response, oxidative stress, heart problems, and lung damage. This thesis explores how the cells lining the blood vessels, the endothelium, contributes to these issues. In particular, it examines the role of the NADPH oxidases; a source of oxidants. The pathways examined in this thesis provide a deeper understanding of influenza pathology that could lead to more innovative and beneficial treatments.


Principal supervisor

Stavros Selemidis

Year of Award


Department, School or Centre


Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences