Monash University
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The role of the 3’ untranslated region in breast cancer

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posted on 2018-11-05, 02:22 authored by ANDREW PATTISON
Our genes and the way in which our genetic code is read makes us who we are. Unfortunately, our genetic code can be altered or misinterpreted in cancer. The 3’ untranslated region is one such example of an important part of our genetic code that is read differently in cancer. This thesis focused on defining what changes to the 3’ untranslated region occur in breast cancer, then explored which of these changes were most associated with breast cancer outcome. Extension and validation of the work in this thesis may one day lead to a better test for breast cancer outcome.


Principal supervisor

Traude Beilharz

Additional supervisor 1

Paul Harrison

Year of Award


Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Biochemistry and Molecular Biology

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences