Monash University

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Reason: Under embargo until April 2025. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

The role of dietary amino acids in shaping Drosophila melanogaster reproduction and lifespan

posted on 2022-04-13, 23:54 authored by JAVIER GOMEZ ORTEGA
A balanced diet is important for good health. One of the dietary components, protein, has been shown to be particularly important since consuming too little restricts growth and reproduction, while consuming too much has been shown to shorten lifespan. Using the easily manipulated lab animal, the fruit fly Drosophila melanogaster, I have found evidence that these constraints have shaped organismal body composition from bacteria to apex predators. I used a novel systems biology approach to find genes mediating the effects of protein on lifespan. My results point to new strategies by which we might use diet to improve lifelong health.


Campus location


Principal supervisor

Matthew Piper

Additional supervisor 1

Christen Mirth

Additional supervisor 2

Sonika Tyagi

Year of Award


Department, School or Centre

Biological Sciences


Doctor of Philosophy

Degree Type



Faculty of Science