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The role of DNA methylation in Obesity and Diabetes

thesis
posted on 2018-02-13, 01:38 authored by ISHANT KHURANA
A significant proportion of human disease causality remains unexplained. It is increasingly becoming clear that Epigenetics is a key contributor to many diseases, including cardiovascular diseases, atherosclerosis and diabetes. Epigenetics refers to the external modification to DNA that turn genes “ON” and “OFF”. These modifications do not change the DNA sequence, but instead, they effect cells ability to “read” genes. This thesis investigates the role of DNA methylation in Obesity and Diabetes.

History

Principal supervisor

Assam El-Osta

Additional supervisor 1

Mark Ziemann

Year of Award

2018

Department, School or Centre

Central Clinical School

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

    Categories

    Keywords

    DNA methylationDiabetesObesityEpigenomicsMethylomeDiseasesMolecular BiologyEpigenetics (incl. Genome Methylation and Epigenomics)

    Licence

    In Copyright

    Exports

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