Paul Mirabella PhD Thesis file_amended.pdf (31.58 MB)
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The mechanistic underpinnings of postprandial thermogenesis in brown fat – the role of glucose-sensing POMC neurons

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thesis
posted on 28.08.2020, 06:19 by PAUL NICHOLAS MIRABELLA
This thesis examines how the brain controls fat-burning following consumption of a meal. It demonstrates that the nutrient, glucose, can be “sensed” by neurons in the brain with assistance from specialised support cells to promote metabolism and the burning of calories. These findings have implications for the treatment of obesity and related metabolic disorders.

History

Principal supervisor

Brian Oldfield

Additional supervisor 1

David Spanswick

Year of Award

2020

Department, School or Centre

Physiology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE