JadeKannangara_Thesis revisions_20_03_20.pdf (13.16 MB)
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The identification and characterisation of novel peptide signalling pathways that function in the Drosophila prothoracic gland

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posted on 27.03.2020, 07:55 by JADE RENATHA KANNANGARA
Developing animals often use steroid hormones to control important transitions in life stages, and dysregulation of such hormones can lead to severe consequences such as delays in development, malformations, or even death. Steroid hormone production is regulated by protein signals produced in the brain, but we have a limited understanding of the range signals used. Using the fruit fly as a model system, this thesis identified several new proteins that regulate steroid hormone synthesis. Reducing the levels of these proteins resulted in impaired steroid hormone production. These findings suggest that regulation of steroids is more complex than previously thought.


Campus location


Principal supervisor

Christen Mirth

Additional supervisor 1

Coral Warr

Additional supervisor 2

Michelle Henstridge

Additional supervisor 3

Linda Parsons

Year of Award


Department, School or Centre

Biological Sciences


Doctor of Philosophy

Degree Type


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