Monash University

Embargoed and Restricted Access

Reason: Under embargo until July 2018. After this date a copy can be supplied under Section 51 (2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

The epidemiology of fluid administration, fluid accumulation and fluid balance in the critically ill and the relationship between intravenous fluid therapy and patient-centred outcomes.

posted on 2017-07-19, 00:01 authored by NEIL JOHN GLASSFORD
Fluid resuscitation is used every day to treat unstable critically ill patients, but there is little more evidence for its use now than there was in 1832 when it was first reported. Patients who accumulate more fluid than they can eliminate tend to have worse outcomes than those who do not. This thesis explores regional and international approaches to fluid resuscitation, and national trends in fluid use. It also explores the effect of fluid resuscitation on fluid accumulation and how changes in fluid accumulation and fluid elimination impact patient outcomes.


Principal supervisor

Rinaldo Bellomo

Additional supervisor 1

Michael Bailey

Year of Award


Department, School or Centre

Public Health and Preventive Medicine

Additional Institution or Organisation

Australia and New Zealand Intensive Care Research Centre

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences