Monash University
Thesis (Maryam Hassanzahraee).pdf (35.77 MB)
Download file

The effects of anodal transcranial direct current stimulation on cortical and behavioural changes: An investigation of counter-regulatory mechanisms

Download (35.77 MB)
posted on 2021-02-24, 21:48 authored by MARYAM HASSANZAHRAEE
Transcranial direct current stimulation (tDCS) is a non-invasive brain neuromodulatory technique for induction of changes in the activity and excitability of the brain. Long term potentiation- (LTP) like plasticity is induced when anodal tDCS (a-tDCS) is applied over the primary motor cortex. It has been shown that specific parameters of a-tDCS can induce different effects on corticospinal excitability (CSE) in different individuals. While, not much is known about the exact stimulation parameters for reversals, and non-linearities, as well as underlying mechanisms, therefore, the studies introduced in this thesis are motivated by the need to explore if changing duration and intensity of stimulation would affect the effect of a-tDCS on CSE and even reverse it. Moreover, it was aimed to investigate if changes on CSE following a-tDCS would affect a motor performance task.


Principal supervisor

Shapour Jaberzadeh

Additional supervisor 1

Maryam Zoghi

Year of Award


Department, School or Centre


Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine, Nursing and Health Sciences