Thesis_Shuqi Chen_Final.pdf (51.26 MB)
The development of methods for the rapid assembly of diverse sp2- and sp3-rich scaffolds
thesisposted on 2023-07-17, 02:03 authored by SHUQI CHEN
Novel 2-dimensional (sp2-rich) and 3-dimensional(sp3-rich) chemical scaffolds have great potential in drug discovery and material science but limited methods for their preparation. This thesis examines the current limitations in their synthesis and develops robust synthetic methods for the rapid assembly of these sp2- and sp3-structures through iodocyclization and Nazarov cyclization, respectively.