File(s) under permanent embargo

Reason: Under embargo until October 2019. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library or by emailing

The Role of Macrophages in Neonatal Lung Injury Induced By Hyperoxia: Effects of Human Mesenchymal Stem Cells

posted on 23.10.2018, 22:46 by ALI HANI ABD AL-RUBAIE
The effects of the inhaled exposure to high oxygen in preterm babies that require supplemental oxygen to survive was studied. Neonatal mice were exposed to high oxygen for the first week of life to promote an inflammatory response in the lung. Mice were administered human bone marrow stem cells into the airways, followed by assessment of infiltrating lung immune cells response and the severity of lung fibrosis. The use of these stem cells presents an effective treatment for hyperoxia-induced neonatal lung injury due to homing of the cells to the injured lung tissue and alteration of lung immune cells to ameliorate injury.


Principal supervisor

Sharon Ricardo

Additional supervisor 1

Richard Harding

Additional supervisor 2

Foula Sozo

Year of Award


Department, School or Centre

Anatomy and Developmental Biology

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences

Usage metrics