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The Pathogenesis of Proteinase 3 ANCA-Associated Vasculitis

thesis
posted on 2023-11-28, 04:37 authored by ILANA RACHEL SHOCHET
ANCA-associated vasculitis is a rare but serious autoimmune disease, which causes inflammation and damage to blood vessels particularly in the kidneys and lungs. Treatment involves toxic medications, which can cause serious side effects and often must be continued for many years. Significant knowledge gaps exist in the field, including understanding the mechanism of risk of identified genetic risk factors for disease development. This thesis considers how and why this disease develops, suggests alternative methods for more accurate diagnosis and monitoring, and looks to exciting potential treatments which aim to treat autoimmune diseases at their source.

History

Principal supervisor

Arthur Richard Kitching

Additional supervisor 1

Dr Maliha Alikhan

Year of Award

2023

Department, School or Centre

Medicine - Monash Health

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

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