Pedro_PhD_Thesis.pdf (34.21 MB)
Download file

The NFY transcription factor complex controls nervous system development in Caenorhabditis elegans

Download (34.21 MB)
thesis
posted on 21.12.2020, 03:49 by PEDRO MIGUEL LOPES MOREIRA
Correct establishment of brain architecture during development is a complex process that requires precise control of cell specification, migration, and axo-dendritic guidance. These events are regulated by multiple transcription factors, guidance systems, and environmental cues. In this work, I identified a molecular network through which the NFY complex directly regulates both neuron-type specific and pan-neuronal gene signatures.

History

Principal supervisor

Roger David John Pocock

Year of Award

2020

Department, School or Centre

Anatomy and Developmental Biology

Course

Doctor of Philosophy

Degree Type

DOCTORATE