The NFY transcription factor complex controls nervous system development in Caenorhabditis elegans
thesisposted on 2020-12-21, 03:49 authored by PEDRO MIGUEL LOPES MOREIRA
Correct establishment of brain architecture during development is a complex process that requires precise control of cell specification, migration, and axo-dendritic guidance. These events are regulated by multiple transcription factors, guidance systems, and environmental cues. In this work, I identified a molecular network through which the NFY complex directly regulates both neuron-type specific and pan-neuronal gene signatures.