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The NFY transcription factor complex controls nervous system development in Caenorhabditis elegans

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posted on 2020-12-21, 03:49 authored by PEDRO MIGUEL LOPES MOREIRA
Correct establishment of brain architecture during development is a complex process that requires precise control of cell specification, migration, and axo-dendritic guidance. These events are regulated by multiple transcription factors, guidance systems, and environmental cues. In this work, I identified a molecular network through which the NFY complex directly regulates both neuron-type specific and pan-neuronal gene signatures.


Principal supervisor

Roger David John Pocock

Year of Award


Department, School or Centre

Anatomy and Developmental Biology


Doctor of Philosophy

Degree Type