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The NFY transcription factor complex controls nervous system development in Caenorhabditis elegans

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thesis
posted on 2020-12-21, 03:49 authored by PEDRO MIGUEL LOPES MOREIRA
Correct establishment of brain architecture during development is a complex process that requires precise control of cell specification, migration, and axo-dendritic guidance. These events are regulated by multiple transcription factors, guidance systems, and environmental cues. In this work, I identified a molecular network through which the NFY complex directly regulates both neuron-type specific and pan-neuronal gene signatures.

History

Principal supervisor

Roger David John Pocock

Year of Award

2020

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Anatomy and Developmental Biology

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences