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The Effect of Chronic Social Stress on Phoenixin-20 Gene Expression and Protein Profiling in the Midbrain of the Male Nile Tilapia (Oreochromis niloticus).

thesis
posted on 2023-12-15, 08:18 authored by BOON LEE CHIAM
This thesis examines the expression of the pnx-20 and gpr173 both before and after exposing O. niloticus to chronic social stress. Following that, it also constructs protein profiling in chronic social stress induced animals and followed by the phoenixin-20 peptide treatment. In chronic social stress exposed animals, both gene expression of pnx-20 and gpr173 decreased significantly in Area A while only pnx-20 in Area B. While the protein-protein interaction (PPI) analysis yielded three clusters: carbohydrate metabolism and RNA degradation (cluster 1), amino acid metabolism and biosynthesis (cluster 2), and TCA cycle (cluster 3).

History

Principal supervisor

Faizul Jaafar

Additional supervisor 1

Tomoko Soga

Additional supervisor 2

Mageswary Sivalingam

Year of Award

2023

Department, School or Centre

Jeffrey Cheah School of Medicine and Health Sciences (Monash University Malaysia)

Campus location

Malaysia

Course

Master of Biomedical Science

Degree Type

MPHIL

Faculty

Faculty of Medicine, Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

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