The Effect of Chronic Social Stress on Phoenixin-20 Gene Expression and Protein Profiling in the Midbrain of the Male Nile Tilapia (Oreochromis niloticus).
thesis
posted on 2023-12-15, 08:18authored byBOON LEE CHIAM
This thesis examines the expression of the pnx-20 and gpr173 both before and after exposing O. niloticus to chronic social stress. Following that, it also constructs protein profiling in chronic social stress induced animals and followed by the phoenixin-20 peptide treatment. In chronic social stress exposed animals, both gene expression of pnx-20 and gpr173 decreased significantly in Area A while only pnx-20 in Area B. While the protein-protein interaction (PPI) analysis yielded three clusters: carbohydrate metabolism and RNA degradation (cluster 1), amino acid metabolism and biosynthesis (cluster 2), and TCA cycle (cluster 3).
History
Principal supervisor
Faizul Jaafar
Additional supervisor 1
Tomoko Soga
Additional supervisor 2
Mageswary Sivalingam
Year of Award
2023
Department, School or Centre
Jeffrey Cheah School of Medicine and Health Sciences (Monash University Malaysia)