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The Development of Novel Biased Allosteric Ligands of the Metabotropic Glutamate Receptor Subtype 5

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posted on 2025-11-23, 22:03 authored by Scott Wong
This research thesis explores the computer-aided design, chemical synthesis and biochemical testing of novel molecules that target a CNS protein to aid in the development of safe drugs for neurological disorders, including Alzheimer's disease and schizophrenia.

History

Campus location

Australia

Principal supervisor

Ben Capuano

Additional supervisor 1

Karen J. Gregory

Additional supervisor 2

Peter J. Scammells

Year of Award

2025

Department, School or Centre

Medicinal Chemistry

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Pharmacy and Pharmaceutical Sciences

Rights Statement

The author retains copyright of this thesis. It must only be used for personal non-commercial research, education and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission. For further terms use the In Copyright link under the License field.

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    Faculty of Pharmacy and Pharmaceutical Sciences Theses

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