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Reason: Under embargo until June 2019. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library
Targeting macrophage function in hypertension
thesis
posted on 2018-06-04, 04:44 authored by ANNA WANGHigh blood pressure, also known as hypertension, is the leading risk factor for cardiovascular diseases. The immune system is thought to promote hypertension through inflammation of blood vessels, through the action of immune cells called macrophages. This project discovered that macrophages may promote the growth of nerves around blood vessels, causing them to contract more powerfully and contribute to hypertension. Additionally, drugs that target a protein caused the angiotensin type 2 receptor can reduce the release of molecules from macrophages that promote inflammation and may be a new approach to treating inflammation associated with hypertension.