Monash University

Embargoed and Restricted Access

Reason: Under embargo until November 2024. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Tailoring proteins as efficient binders for health and environmental applications

posted on 2021-11-23, 20:25 authored by GINA PACHECO ARREDONDO
Molecular binders play important roles in biology and biotechnology. They are widely used in health, biomaterials and environmental sectors. Protein-based binders have attracted significant interest due to their desirable features like biocompatibility and their potential to be engineered for binding broad range molecule. While protein engineering is a powerful tool, it has not yet been fully exploited to improve functionalities of proteins as binders. Herein, this thesis explores tailoring proteins to suit a variety of different applications including the recovery of small molecules for environmental and diagnostic applications, removal of large and toxic molecules, or neutralization of viruses.


Campus location


Principal supervisor

Lizhong He

Additional supervisor 1

Stephen Holt

Year of Award


Department, School or Centre

Chemical & Biological Engineering

Additional Institution or Organisation

Chemical Engineering


Doctor of Philosophy

Degree Type



Faculty of Engineering