File(s) not publicly available

Reason: Under embargo until September 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library, or by emailing

T cell polarisation in the Preterm Infant and its Impact on Bronchopulmonary Dysplasia

posted on 03.09.2019 by CHUN WANG JASON LAO
The chronic lung disease BPD is common in preterm babies, i.e. those born about two-thirds through a normal pregnancy. These babies are dependent on supplemental oxygen for months to years, and their doctors have no effective therapy. I examined blood samples from 51 preterm babies at birth and 4 other time points and found that BPD babies have specific immune polarisation patterns. This finding provides a new understanding of the process driving BPD and lays the foundation for repurposing of a group of existing medicines for use in these tiny patients, bringing hope for relief from this devastating disease.


Principal supervisor

Marcel Nold

Additional supervisor 1

Claudia Nold

Additional supervisor 2

Ina Rudloff

Additional supervisor 3

Niamh Mangan

Year of Award


Department, School or Centre


Additional Institution or Organisation

Hudson Institute of Medical Research

Campus location



Doctor of Philosophy

Degree Type