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Reason: Under embargo until February 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Systems Pharmacology of Lipid A Modifications Associated with Polymyxin Resistance in Gram-negative Bacteria

thesis
posted on 2021-02-04, 21:13 authored by Jiayuan Huang
Antibiotic resistance is a significant global medical challenge. This thesis identifies complex bacterial responses to polymyxin treatment and enhances our understanding of the mechanisms of resistance. This study provides key mechanistic information for optimisation of polymyxin therapy in patients.

History

Principal supervisor

Jian Li

Additional supervisor 1

Tony Velkov

Additional supervisor 2

Chen Li

Additional supervisor 3

Yan Zhu

Year of Award

2021

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Microbiology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences