Reason: Access restricted by the author. A copy can be requested for private research and study by contacting your institution's library service. This copy cannot be republished
Synthesis of fatty acid-terminated polymers by copper-mediated polymerization for drug delivery applications
thesisposted on 2021-01-09, 23:37 authored by ALEXANDER MOERSDORF
A library of lipid-terminated ATRP-initiators and polymers based on PEG were synthesized. The self-assembly of the amphiphilic PEG-polymers was studied, as well as their binding to bovine serum albumin. Cytotoxic studies and pharmacokinetics proved their capability to serve as drug delivery devices after binding to albumin.