Synthesis, Characterisation, and Biological Evaluation of Novel Metal Flavonolate Complexes

Flavonols are molecules of plant origin with diverse therapeutic properties. This work explored the synthesis and biological evaluation of flavonolate complexes with medicinally-relevant metals, namely: gallium, indium, and bismuth. Important structural features that determine the solubility and biological activity of the respective metal-flavonolate complexes were elucidated; providing a foundation for the rational design of effective metal-based antibacterial and anticancer agents.