Structural MRI Biomarkers of Stereo-electroencephalography Defined Epileptogenicity

This thesis examines whether additional post-processing of brain scans (MRI) is linked to the location of the epileptogenic zone (EZ) in drug-resistant epilepsy patients with implanted stereotactic EEG (SEEG). We found that increased gray matter volume was related to the EZ in patients with significant MRI lesions. Additionally, we observed that enlarged hippocampal and amygdala volumes were associated with hippocampi that are part of the EZ despite the absence of visible lesions. Overall, these findings enhance our understanding of how we can utilize these MRI scans to identify patients who may benefit from epilepsy surgery.