Monash University
Browse

Structural Characterisation of P-Rex Activity and Dysregulation in Cancer

thesis
posted on 2018-05-02, 02:45 authored by CHRISTINA MARY ANNA LUCATO
This thesis examines the molecular structure of the P-Rex family of proteins. It explains the mechanism of activity and regulation that allow these molecules to drive tumor growth and metastasis.

History

Principal supervisor

Andrew Ellisdon

Additional supervisor 1

Michelle Halls

Additional supervisor 2

James Whisstock

Year of Award

2018

Department, School or Centre

Biomedical Sciences (Monash Biomedicine Discovery Institute)

Additional Institution or Organisation

Biochemistry and Molecular Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

Usage metrics

    Faculty of Medicine, Nursing and Health Sciences Theses

    Categories

    Keywords

    X-ray crystallographyElectron microscopyP-RexCancerCell signallingStructural Biology

    Licence

    In Copyright

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC