L50 Doctoral Thesis_Revised_Trina Majumdar_Redacted.pdf (59.78 MB)

Strategies for the improvement of Ti-6Al-4V implant osseointegration

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thesis
posted on 12.03.2019, 22:53 by TRINA MAJUMDAR
Titanium-based alloys are used extensively in orthopaedic implants due to their low cytotoxicity and high mechanical strength. However these issues can also limit full implant functionality, particularly for patients with complex orthopaedic issues. The surfaces of Ti-based implants do not typically induce strong mechanical interlocking, and the elastic modulus mismatch between the implant and host bone can lead to stress shielding and bone resorption. These issues often necessitate painful and costly revision surgeries. Major strategies in solving these problems include the use of alternate fabrication processes such as selective laser melting (SLM), surface coating with bone-like minerals, and the use of hydrogels as temporary intermediaries between the implant and growing host tissue.

History

Campus location

Australia

Principal supervisor

Nick Birbilis

Additional supervisor 1

Jessica Ellen Frith

Year of Award

2019

Department, School or Centre

Materials Science and Engineering

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering

Exports

Exports