Monash University

Embargoed and Restricted Access

Reason: Under embargo until August 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library

Social and clinical studies of interventions towards HIV cure

posted on 2021-08-25, 13:24 authored by JILLIAN SHU YUN LAU
This thesis explores the field of HIV cure: efforts to control or eradicate the virus in the absence of regular treatment. There is a particular focus on clinical trials of interventions that withhold HIV treatment as a test of whether the intervention works. This practice is known as an analytical treatment interruption. Stakeholder perceptions of trial involving these interruptions were explored. Alternative trial designs have been proposed that balance statistical power with safety and convenience of participants. Additionally, the role of drugs typically used in cancer therapy were studied as an HIV cure intervention. This thesis provides new insights and knowledge vital for the advancement of HIV cure science.


Principal supervisor

James Mcmahon

Additional supervisor 1

Sharon Lewin

Year of Award


Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Alfred Hospital, Central Clinical School, Monash University

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine, Nursing and Health Sciences

Usage metrics

    Faculty of Medicine, Nursing and Health Sciences Theses