File(s) under permanent embargo

Reason: Under embargo until August 2022. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library, or by emailing document.delivery@monash.edu

Social and clinical studies of interventions towards HIV cure

thesis
posted on 25.08.2021, 13:24 by JILLIAN SHU YUN LAU
This thesis explores the field of HIV cure: efforts to control or eradicate the virus in the absence of regular treatment. There is a particular focus on clinical trials of interventions that withhold HIV treatment as a test of whether the intervention works. This practice is known as an analytical treatment interruption. Stakeholder perceptions of trial involving these interruptions were explored. Alternative trial designs have been proposed that balance statistical power with safety and convenience of participants. Additionally, the role of drugs typically used in cancer therapy were studied as an HIV cure intervention. This thesis provides new insights and knowledge vital for the advancement of HIV cure science.

History

Principal supervisor

James Mcmahon

Additional supervisor 1

Sharon Lewin

Year of Award

2021

Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Alfred Hospital, Central Clinical School, Monash University

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Usage metrics

Categories

Exports