Monash University

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Reason: Under embargo until 30 June 2024. After this date a copy can be supplied under Section 51(2) of the Australian Copyright Act 1968 by submitting a document delivery request through your library.

Role of sirtuins in the regulation of Toxoplasma gondii interconversion between tachyzoite and bradyzoite cysts

posted on 2023-06-21, 03:25 authored by KARL VERN TAN
The high prevalence of Toxoplasma gondii infection in the worldwide human population (30%) is mainly due to the ability of the proliferative stage parasite to convert into latent tissue cysts. To date, there are no effective treatments available to treat and control the spread of this disease, and the stage conversion mechanism of the parasite remains unclear. This thesis investigates the role of sirtuin in modulating the stage conversion process. The findings in the present study suggest that T.gondii sirtuin may not play a role in regulating the interconversion process.


Campus location


Principal supervisor

Chow Sek Chuen

Additional supervisor 1

Yeong Ken Yoon

Year of Award


Department, School or Centre

School of Sciences (Monash University Malaysia)


Doctor of Philosophy

Degree Type



Faculty of Science

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    Faculty of Science Theses