Role of Casein Kinase 1 of Plasmodium falciparum in parasite biology and as a target for novel anti-malarial drugs

Plasmodium falciparum causes the most lethal form of malaria in humans, resulting in hundreds of thousands of deaths every year and this is likely to increase with the emergence of drug resistance. This thesis investigates how the malaria parasite manipulates its host during infection and identifies new processes that allow the parasite to traffic its proteins and cause disease, thereby opening new avenues for the exploration of potential therapeutic targets.