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Repurposing drugs to improve chemotherapy outcomes in breast cancer

thesis
posted on 31.07.2020 by AESON CHANG
Breast cancer impacts many lives. Cognitive side effects and poor survival in women with breast cancer remain significant clinical challenges. This thesis 1) identifies unanticipated effects of chemotherapy on nerves and receptors that regulate the stress response which adversely impacts survival; and 2) clarifies the role of inflammation in cognitive side effects caused cancer and chemotherapy. This thesis highlights the opportunity to repurpose readily available drugs to improve the effects of chemotherapy on the cognition and survival of women with breast cancer

History

Campus location

Australia

Principal supervisor

Erica Kate Sloan

Additional supervisor 1

Adam K Walker

Year of Award

2020

Department, School or Centre

Drug Discovery Biology

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Exports

Exports