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Regulation & Function of Reactive Astrocytes in the Primate Brain: A Novel Role for NogoA

thesis
posted on 09.10.2019, 04:30 by ANTHONY GEORGE BOGHDADI
This thesis explores the regulation and function of injury-responsive support cells in the brain after injury. It demonstrates that age-dependent differences in support cell regulation are responsible for the better capacity for younger brains to recover after brain injuries, compared to adults. It also identifies a never before described link between these support cells and a major blocker of brain repair, contributing to suppressing inflammation following stroke. These findings have clinical implications for the development and testing of treatment strategies for brain injuries.

History

Principal supervisor

James Bourne

Additional supervisor 1

Leon Teo

Year of Award

2019

Department, School or Centre

Australian Regenerative Medicine Institute (ARMI)

Additional Institution or Organisation

Australian Regenerative Medicine Institute

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

Exports