Monash University

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Proteomic biomarkers of azoospermia in seminal plasma and testicular interstitial fluid

posted on 2022-03-09, 23:37 authored by RAOUDA SGAIER
There is an unmet clinical need for more accurate, less invasive diagnosis methods for severe forms of male infertility, such as azoospermia. We analysed seminal plasma and testicular fluid from men diagnosed with different forms of infertility to better our understanding of these conditions and identify markers of male reproductive potential. We were able to see significant differences in protein expression between fertile men and infertile men diagnosed with varying degrees of testicular failure, and we identified several proteins that could serve as proteomic biomarkers for the differential diagnosis of idiopathic male infertility.


Principal supervisor


Year of Award


Department, School or Centre

Central Clinical School

Additional Institution or Organisation

Molecular and Translational Science (Hudson Institute)


Doctor of Philosophy (Joint PhD with Justus Liebig University Giessen - International)

Degree Type



Faculty of Medicine, Nursing and Health Sciences