L161 ChengHuang_Revised_Thesis_Redacted.pdf (6.19 MB)
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Proteomic and phosphoproteomic studies of monocyte recruitment and macrophage polarisation

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posted on 2019-03-26, 00:09 authored by CHENG HUANG
The balance between inflammatory and anti-inflammatory monocytes and macrophages, specialised white blood cells, is important in the development versus resolution of inflammatory diseases like atherosclerosis. This thesis describes studies of the global protein profiles in different types of macrophages and to investigate the mechanism of monocytes and macrophages being recruited to the sites of inflammation. This thesis will contribute to an improved understanding of monocyte recruitment and will guide the development of effective atherosclerosis therapies


Principal supervisor

Martin Stone

Additional supervisor 1

Ralf Schittenhelm

Year of Award


Department, School or Centre

Biochemistry and Molecular Biology

Additional Institution or Organisation

Biomedicine Discovery Institute

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences