Monash University
PhD Thesis -Pradeep Gc 2018.pdf (9.78 MB)

Protein-based functional nanoparticles: Comparision of strategies for design and engineering

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posted on 2018-10-19, 03:45 authored by PRADEEP G C
This Ph.D. thesis focuses on engineering protein-based functional nanoparticles that have attractive structural and functional properties. Different strategies in designing and engineering such nanoparticles have been studied and compared. The strategies include: i) covalent immobilisation of protein on silica nanoparticles, ii) non-covalent affinity immobilisation of proteins on silica and iron oxide nanoparticles, iii) self-assembly peptides for formation of protein-only nanoparticles, and iv) combination of self-assembly and affinity adsorption to form clusters of hybrid protein-iron oxide nanoparticles. This research has built a new platform for designing protein-based functional nanomaterials that may have diverse application in biomedical, health, and environmental sectors.


Campus location


Principal supervisor

Lizhong He

Additional supervisor 1

Geoff Dumsday

Additional supervisor 2

Victoria Haritos

Year of Award


Department, School or Centre

Chemical & Biological Engineering

Additional Institution or Organisation

Chemical Engineering


Doctor of Philosophy

Degree Type



Faculty of Engineering