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Profiling the diversity, bioactivity and metabolomic analysis of endolichenic fungi from Malaysia and the Philippines
thesisposted on 2020-06-12, 10:20 authored by KRYSTLE ANGELIQUE AGUDA SANTIAGO
This research involves the lichen Usnea, from Malaysia and the Philippines, and fungi living inside the lichen called endolichenic fungi (ELF). Results revealed that Usnea is a home for diverse ELF. The application of lichens and ELF in combating different microbes were also highlighted, revealing the ability of ELF in targeting a bigger group of microbes than lichens. Using a modern technology called metabolomics, a bioactive compound new to ELF was discovered and found responsible for its strong antibacterial activity. This research is the first assessment of the diversity and bioactivity of ELF from Usnea in Malaysia and the Philippines.