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Patterns of Care and Novel Therapeutics for Multiple Myeloma

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thesis
posted on 2022-09-08, 02:17 authored by KRYSTAL FRANCES BERGIN
Multiple myeloma (MM), an incurable mature B-cell neoplasm is the second most common haematological malignancy. MM research is largely derived from clinical trial data of highly selected patient populations. This thesis investigated if these patient populations accurately reflect “real-world” myeloma patient populations in Australia/New Zealand and therefore the appropriateness of extrapolation of these data. This was achieved by in-depth interrogation of data from the Myeloma and Related Diseases Registry. Additionally, this thesis evaluated novel therapies in relapsed/refractory (RR)MM including a clinical trial investigating the combination of ixazomib, thalidomide and dexamethasone, a new, all oral, more affordable therapy combination for RRMM.

History

Principal supervisor

Andrew Spencer

Additional supervisor 1

Erica Wood

Additional supervisor 2

Elizabeth Moore

Year of Award

2022

Department, School or Centre

Australian Centre for Blood Diseases

Additional Institution or Organisation

Clinical Haematology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine, Nursing and Health Sciences

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    Faculty of Medicine, Nursing and Health Sciences Theses

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