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Pathological and genomic features of high-risk prostate cancer

thesis
posted on 07.05.2019 by LAURA HELEN PORTER
Prostate cancer is still associated with substantial morbidity and mortality. To improve survival outcomes, there is a need to identify new biomarkers of high-risk disease. This thesis investigated the sub-pathology intraductal carcinoma of the prostate (IDC-P), demonstrating that IDC-P is prevalent in high-risk prostate cancer and is associated with aggressive growth characteristics. This thesis also explored novel therapeutic strategies, identifying a new combination therapy that is effective for aggressive prostate cancers. This work is significant as it will improve the clinical management of patients with high-risk prostate cancer.

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History

Principal supervisor

Renea Taylor

Year of Award

2019

Department, School or Centre

Anatomy and Developmental Biology

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Medicine Nursing and Health Sciences

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