Final_Lacey_thesis_Pathogenomics_of_necrotic_enteritis_assocaited_Clostridium_perfringens.pdf (5.5 MB)
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Pathogenomics of Necrotic enteritis associated Clostridium perfringens

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posted on 2018-03-18, 22:51 authored by JAKE AIDAN LACEY
The bacterial pathogen, Clostridium perfringens, causes necrotic enteritis, an intestinal disease of chickens. This disease is of concern to the global poultry industry. C. perfringens can also cause diseases in other animals, including humans. In this thesis, the genetic structure of a collection of C. perfringens strains was analysed and correlated with the different abilities of these strains to cause disease. It was established that significant genetic differences exist between strains and that transfer of genes between bacteria may contribute to the emergence and spread of new virulent strains of bacteria.


Principal supervisor

Dena Lyras

Additional supervisor 1

Robert Moore

Additional supervisor 2

Priscilla Johanesen

Year of Award


Department, School or Centre


Additional Institution or Organisation

Poultry CRC, CSIRO

Campus location



Doctor of Philosophy

Degree Type



Faculty of Medicine Nursing and Health Sciences