Optimising Bone and Reproductive Health in Individuals with Type 1 Diabetes

This body of work presented in this thesis explores the impact of type 1 diabetes on the skeletal and reproductive systems, including the diverse mechanisms behind bone fragility and reproductive disorders, as well as the bi-directional interactions between reproductive, bone and metabolic health. There is an increased risk of fracture and reproductive disorders in women with type 1 diabetes, which merits greater awareness amongst clinicians and patients, with opportunities for timely identification and optimisation of risk factors.