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On Developing Effective Nanoparticle-Based Vaccines Against Malaria

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posted on 2018-02-26, 00:11 authored by LIAM MICHAEL POWLES
Malaria is still a major problem in many regions of the world, causing thousands of deaths a year. With the effectiveness of current control strategies declining, vaccination is a possible long-term solution. Current malaria vaccines are not strong enough to provide protection. Therefore, improved methods to deliver and improve vaccines are required. Binding vaccines to the surface of nanoparticles is one such method. In this work, iron oxide nanoparticles are produced and tested as vaccine delivery vehicles. These nanoparticles greatly improved the effectiveness of different vaccines, providing a basis for future malaria vaccine studies.

History

Campus location

Australia

Principal supervisor

Cordelia Selomulya

Additional supervisor 1

Magdalena Plebanski

Additional supervisor 2

Sue D Xiang

Year of Award

2018

Department, School or Centre

Chemical & Biological Engineering

Additional Institution or Organisation

Chemical Engineering

Course

Doctor of Philosophy

Degree Type

DOCTORATE

Faculty

Faculty of Engineering

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