On Developing Effective Nanoparticle-Based Vaccines Against Malaria

Malaria is still a major problem in many regions of the world, causing thousands of deaths a year. With the effectiveness of current control strategies declining, vaccination is a possible long-term solution. Current malaria vaccines are not strong enough to provide protection. Therefore, improved methods to deliver and improve vaccines are required. Binding vaccines to the surface of nanoparticles is one such method. In this work, iron oxide nanoparticles are produced and tested as vaccine delivery vehicles. These nanoparticles greatly improved the effectiveness of different vaccines, providing a basis for future malaria vaccine studies.