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Novel approaches for modulating endogenous plasmalogens: applications to the treatment of metabolic disease

thesis
posted on 05.04.2020, 22:55 by SUDIP PAUL
Plasmalogens are membrane lipids with numerous biological activities. Considering their reduced levels in disease conditions, modulation of endogenous plasmalogen levels has been suggested as a potential therapeutic strategy. However, an optimal plasmalogen modulation approach has not been defined. This thesis proposes novel dietary and genetic approaches for productive and precise modulation of endogenous plasmalogens which may be an effective therapy for prevention, attenuation and treatment of metabolic disease.

History

Principal supervisor

Peter

Additional supervisor 1

Graeme Lancaster

Year of Award

2020

Department, School or Centre

Medicine - Alfred

Additional Institution or Organisation

Baker Hear and Diabetes Institute

Campus location

Australia

Course

Doctor of Philosophy

Degree Type

DOCTORATE